Posts Tagged ‘Parkinson’

Are musculoskeletal problems in Parkinson’s disease neglected

Parkinson’s disease – PD patients do not receive adequate treatment for musculoskeletal problems. This was the conclusion reached by Kim YE et al. from the Department of Neurology and Movement Disorder Center, Parkinson Study Group, Seoul National University Hospital, Seoul, Republic of Korea.

The researches found the prevalence of musculoskeletal problems was significantly higher in the Parkinson disease (PD) group compared to controls. However these musculoskeletal problems in the PD group tended to receive less treatment than that of the control group despite PD patients having a higher prevalence than in the controls.

The contribution of movement activation and inhibition in Parkinson’s Disease

Writing in Journal of Parkinson’s Disease, 05/08/2013 Disbrow EA et al.use functional magnetic resonance imaging (fmri) to look at  circuits within the basal ganglia that coordinate activation and inhibition involved in action selection as well as execution in PD patients. The researchers are from the VA Northern California Health Care System, CA, USA and the Department of Neurology, UC Davis, CA, USA.


Motor and non motor symptoms of Parkinson’s Disease (PD)

Non motor symptoms NMS of Parkinson’s Disease (PD) include sleep dysfunction, dementia and depression and these are key determinants of patients’ health-related quality of life (HRQoL).

Parkinson’s disease (PD) is characterized by a progressive degenerative disorder with both motor symptoms, such as bradykinesia, rest tremor, and rigidity and also non-motor symptoms (NMS). Both motor and NMS contribute to significant morbidity and disability.
Writing in European Journal of Neurology, 04/23/2013 Dr. Martinez and his colleagues from National Parkinson Foundation Centre of Excellence and Institute of Neurology, Kings College Hospital London, United Kingdom discuss the performance of the Movement Disorder Society–Unified Parkinson’s Disease Rating Scale (MDS–UPDRS): Part I – Non–Motor Aspects of Experiences of Daily Living (nM–EDL) and compare this with the Non–Motor Symptoms Scale (NMSS).

Freezing of Gait (FOG) symptoms in Parkinson’s Disease (PD)

The triad of motor disability, cognitive processing speed and affective symptoms are all significant independent predictors of scores on the freezing of gait.

This conclusion was reached by Shine JM et al and published in Parkinson’s Disease Research Clinic, Brain & Mind Research Institute, University of Sydney, Australia.
Motor function was scored on section three of the Unified Parkinson’s Disease Rating Scale questionnaire. A 5-choice reaction time task scored the cognitive processing speed and the Beck Depression Inventory assessed affective disturbance. These scores were compared with Parkinson’s disease patients answers to the self-reported FOG symptoms questionnaire.


Adjunct therapy to improve Parkinsonian disease motor signs

Sponsored by the Movement Disorder Society a trial shows thatstretching, balance, and strengthening exercise program for 2 days per week for 24 months is more effective when combined with a progressive resistance exercise (PRE) (with free weights) program for Parkinsons disease (PD) motor symptoms . The outcome measure used was the Unified Parkinson’s Disease Rating Scale, motor subscale (UPDRS-III).

The report was co-authored by the department of Neurological Sciences, Rush University Medical Center and published in Movement Disorders, 04/16/2013.

Parkinson’s disease (PD) and regulation of amplitude of step length during walking

Is reduced step length and not step length variability central to gait hypokinesia in people with Parkinsons disease PD? Mak MKY et al from Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China writing in Clinical Neurology and Neurosurgery, 04/15/2013 look to answer this question. The researchers compared Parkinson’s disease (PD) patients walking at the same speed as a control group. PD patients and showed that their walking impairment was due to a fundamental problem in regulating the amplitude of step length during walking and not an impairment in step length variability.


Predicting driving ability in PD patients Parkinsons Disease

Predicting driving ability in Parkinsons Disease patients is discussed in the Journal of Parkinson’s Disease, 04/09/2013. Dr. Crizzle AM et al from the Department of Occupational Therapy, University of Florida, Gainesville, FL, USA  compare the predictive power of the unified Parkinson’s Disease Rating Scale (UPDRS) motor section, the Modified Hoehn and Yahr and the Rapid Paced Walk Test to the pass to fail outcome of a formal road test in PD drivers.

The group that look at movement Disorders and neurorestoration together with the Department of Neurology, University of Florida, Gainesville, FL, USA conclude that the gold standard for screening should always be the road test.