Antidepressant Medications and Improvement in Clinical Outcomes After Stroke

Physical therapy

There is renewed interest in the use of antidepressants after stroke firstly because of better knowledge of poststroke depression and secondly the action of some antidepressants in promoting functional recovery of nondepressed patients following stroke.  The authors hypothesize that the link between the fact that antidepressants have the potential to promote functional recovery of nondepressed subjects maybe due to brain plasticity being modulated by external factors such as pharmacological antidepressant agents. It is thus the brain plasticity that is improving recovery and reducing the final disability of patients.

Intensive and regular controlled exercise practice is also known to improve functional outcome of stroke patients. Physical and occupational therapists therefore need to customize the dose and exercise practice to the patients movement ability in order to keep the patient motivated to continue exercise practice.


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